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          ALK (T1151, L1152insT Mutant) Proteins

          ALK (T1151, L1152insT Mutant) Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us... ALK (T1151, L1152insT Mutant) Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... ALK (T1151, L1152insT Mutant) Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.... ALK (T1151, L1152insT Mutant) Human recombinant proteins. Available Product Grades: Research Use Only. Browse 1 protein. Not finding the exact protein, grade or size needed? Contact us to discuss your specific application and product needs.

          Protein Information

          ALK receptor tyrosine kinase or anaplastic lymphoma kinase was originally identified as a member of the insulin receptor subfamily that acquires transforming capability when truncated and fused to NPM (nucleophosmin) in the t(2;5) chromosomal rearrangement associated with ALCL. Many chromosomal rearrangements leading to enhanced ALK activity have been described and are implicated in a number of cancer types. In the nervous system, ALK in the presence of ligand appears essential for axonal guidance, whereas in the absence of ligand, ALK expression can lead to developmental neuronal apoptosis.

          Synonyms

          ALK

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          Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.

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          Invitrogen
          Human ALK [T1151, L1152insT], GST Tag Recombinant Protein
          Invitrogen
          Human ALK [T1151, L1152insT], GST Tag Recombinant Protein
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          Cat # A33509

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